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 |   Related post: sels of the body, moistened and filled, as they are, by alkaline and albuminous fluid, its solvent power is, to a greater or less extent, reduced, and precipitation takes place. It is hence very manifest that no solution but a neutral or alkaline one, or one with great excess of acid, can be expected to escape this THE HYPODERMIC USE OF QUININE. 229 Adjusted Dilantin Level result. He, tlierct'ore, as (►ther exi)eriineiiters in this line be- fore him have done, trutlilully remarks tliat '^ Dilantin Price there is more danger in nsinor too little acid than too much." The addition of carbolic acid to Dr. Lente's formula, lie Generic Dilantin regards as giving additional security against accidents, though he suspects it to be the cause of a more or less extensive numb- ness about the point of puncture, witnessed in his cases. We regard Dilantin 100 Mg it as the application of another delusive but extensive therapeutic fashion of the times. Few substances have ever enjoyed a more specious repute and confidence Dilantin Therapeutic Level among the pro- fession than carbolic acid. Dr. Lente's solution, we Dilantin Generic believe, would be better without it. We do not wish to be understood as denying therapeutic value to carbolic acid. If appropriately applied it is valuable, and we frequently prescribe it. That the general practitioner may comprehend the confu- sion which has resulted from the unscientific and inexact lan- guage used by the experimenters in, and advocates of, hypoder- mic medication with quinine, and perhaps, at the same time, some of the more common causes of the disasters attending it, we will devote a little space to the observation of Dr. Lente, that some of Dilantin Therapeutic Levels these proposed solutions are " extraordinary mixtures." We think it a fair inference that, by this expression, he means us to understand that he cannot see why they should ever have been advocated, as safe and proper, by intelligent and rational men ; that he Dilantin 100 thinks it wonderful that any good results were ever obtained from them. Six years ago, Dr. Dilantin 300 Bartholow, in the "Transactions of the Medical Society of Connecticut," advocated the ethereal solution of quinia. Unsophisticated believers adopted his formula. We will here simply quote what one of them reports of his Dilantin Brand Name results. Of one case he says : " Desiring Dilantin Tablets to rapidly quininize the patient, I injected under the skin of the arms six grains of quinine in ethereal solu- tion." Tumefaction and great soreness followed, and fatal tetanus at the end of twelve days. This was the fourth out of ten cases of the hypodermic use of the solution so much praised by Dilantin Iv Dr. Bartholow, in which this follower had had rea- son to regret resortincr to it. Now, Dr. Lente avers that " quinine is so nearly insoluble 230 THE HYPODEEMIC USE Generic For Dilantin OF QUININE. in ether tliat for all practical purposes it may be so consid- ered." These look like perfectly contradictory declarations, and we mean no disrespect to the average practitioner, when we add that we believe he will so regard them. The facts are, that Dr. Lente refers to the sulphate of quinia, and his statement is true, while Bartholow Dilantin Generic Name means quinia. As regards the reliability of Dr. Bartholow's formula or statement as a practical guide, we prefer to avail ourselves of the statements of practical pharmacists. Neergaard, of this city, whose eminence in this department no one will question, informs us that even were quinia soluble in ether, as the for- mula above referred to leads us to believe, its cost in the mar- ket is about double that of the sulphate, and, therefore, as a matter of economy, would not succeed. But, in fact, the quinia of commerce is but slightly soluble in ether. Hence the elaborate formulae which have at various times and places been published as guides to obtain an ethereal solution of quinia for hypodermic use.^ One will soon be convinced, by consulting these sources of information, that a reliable ethereal solution of quinia is practically unknown, and that medical journal and prize- essay reports of it are a delusion and a snare. And after the strict observance of all these details of chemical manipulation, and a solution Dilantin Capsule of questionable strength and excessive volatility of constituents is obtained, what are the results ? Local inflam- Cost Of Dilantin mation, gangrene, abscesses, tetanus,'' and the very possible ac- cident of throwing the fluid into a vein, where the warmth of the blood would almost certainly volatilize the ether and produce fatal result from heart-paralj^sis. Buy Dilantin An ethereal solution, such as we here refer to, must always, as a chemico-vital fact, be attended by extreme danger of troublesome local accidents, so called; Ether of the strength required for such a solution will coagulate albuminous fluids almost as promptly as nitric acid. Hence such a Dilantin 100mg mixture can- ' ^'■American Journal of Pharmacy^'''' vol. xliii., p. 303, July, 1871, by Charles Rice, Phiirmacist, IJellovuo Hospital, New York. J. C. Wharton, Pharmacist, Nanhville Dilantin Online Journal of Medicine and Surgery^ September, 1873. ^ New Orleans Journal of Medicine^ April, 1870 ; Buy Dilantin Online New York Medical Record^ vol. v., p. 107, June, 1870. 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