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![]() | Related post: When you have a serious case of malaria, so serious that one dose of quinine may be a decid- ing factor in the treatment, I would suggest that you try this plan, using the best method you can work out witl whatever safe material is at hand, watching the result carefully. I think you will give another treatment soon afterwards. THE ORGANISM PROBABLY CAUSING PELLAGRA. By T. E. Sanders, M.D., Citv Health Officer, Hot Spring.s, Ark. On July 14, 1914, I withdrew the spinal fluid from a pellagrin, who had died one hour previous from a violent case of pellagra, ex- hibiting Zithromax Cheap Overnight marked cerebral symptoms. I took all the aseptic precautions that I could. Part of the fluid I examined and the other part I inctibated. The part that I examined showed a very few organisms that appeared to be oval in shape and the periphery stained more intenselv than the center with Giemsa stain. The other part of the spinal fluid was in- ctibated for about a week before it showed any apparent growth. I made a smear and found it to be the same organism. I made a transfer from the growth in the spinal fluid to Agar-Bouillon and Loeffler's Blood Serum. There was no growth on the Agar-Bouillon, but it grew on the blood serum. T kept the growth alive on blood serum by transplant- ing for quite a while then it finally died out. T did not report it publicly for .•'oar that the culture might possibly have been " from con- tamination. On July 31, 1914, a similar case presented itself and I went through the same routine and obtained the same organism. In both cases the organism finally died out on Loeftler's blood serum after many transplants. On October 18, 191 4. I held an autopsy on a pellagrin, who had died of a violent ty- ])hoidal type of pellagra with marked skin le- sions of the wet ulcerative type. The abdom- inal fat was very little, if anv. reduced. The 208 SOUTHERN MEDICAL JOURNAL spleen was comparatively small to the pella- grin's weight. I split the spleen with a sterile knife and inoculated a special media, consist- ing" of a saturated corn meal and agar bouillon faintly acid with hydrochloric acid. Upon cul- turing' I obtained the same organism and it has been growing- upon that special media ever since. The growth upon that media appears as a grayish white, but a slightly darker shade than a growth of typhoid bacilli. It does not spread much on the surface of the media. It is aerobic and requires a great deal of moisture. The organism is highly motile and seems to pass through a definite cycle of some kind. It is characterized by a multiplicity of forms changing from a small oval cell-like form to small bacilli, thread-like bodies, and compara- tively large bacilli. Most anyone upon first examination would naturally think that it was an impure or contaminated culture. Every day it appears different but appears to come back to the same forms. I have been growing it for over four months and the growth ap- pears the same as when it started. It seems reasonable that if it was an impure or con- taminated culture one form would have out- grown and killed out the other. After becoming familiar w'ith the different forms of the organism I began to study a large number of fecal smears that I had gathered from pellagrins in the diarrheal stage of the disease and found that they contained large quantities of the same organism. About the first of last December Mr. Har- vil, a representative of Park Davis Co., re- quested me to let him send the culture to Z Pak Price Without Insurance the P. D. Research Laboratory for investigation. It was sent and they referred it to Dr. Joseph Goldberger of the U. S. Public Health Service. Dr. Goldberger wrote mc that he was sending it back as he was so busy that he did not have any spare time to make the investigation at present. After reading Dr. ?>. \\'. Page's pa])er in the February issue of the SorriTKRN Med- ical JouRXAi. I am convinced that we have both isolated the same organism, although go- ing at it in different methods. AUTHORS' ABSTRACTS. Tropical Diseases and Public Health. Mosquitoes and Sewerage Disposal. By Frederick Knab and August Busch, Washington, Can You Get Zithromax Over The Counter D. C. American Journal of Tropical Diseases and Pre- ventive Medicine, iNovember, 1914, pp. 333-338. Certain species of mosquitoes, particularly Culex pipiens and C. quinquefasciatus, are asso- ciates of man and multiply most rapidly in the presence of highly polluted water. The bearing of this relation on many mosquito outbreaks has not been sufficiently appreciated. The authors present a striking case in that of certain suburbs of one of our large eastern cities, where the install- ment of contrivances for the sanitary disposal of sewage brought with it a great mosnuito invasion. The region is hilly and natural mosquito breeding places conspicuously absent. Two tanks in which the sewage is collected for bacterial reduction were the principal breeding places. In one of these the number of mosquito egg-rafts found floating was estimated at 5,000, with an average of 200 eggs each. Outside of these, mosquitoes were breeding in lesser numbers in many places, but in every case the relation to sewage was obvious. Some small streams were found to con- tain mosquito larvae wherever they were polluted Related links: Buy Crestor, Buy Analgin, online priligy, Buy Colchicine, cheap online diflucan, Benzoyl Peroxide Oxy, Betnovate Gm Cream, tamoxifen buy 20mg, Buy Procyclidine, Purchase Ziprasidone Online
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