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Related post: The coincidence of rhachitis and enlargement of Order Metformin Online the Buy Metformin Online
spleen with hyperplasia of lymph nodes, especially the
mesenteric nodes, was long since noted by Dickinson
and Glisson.
Significance of Enlargement of the Thyreoid in the
Lymphatic Constitution. — In nine of the seventeen eases
collected by Kundrat, in three of seven referred to by
Paltauf, and in one of the writer's two cases — i. e., in
more than fifty per cent, of twenty-six cases — the thy-
reoid gland was found enlarged. Of Buy Metformin the significance
of the goitre in this connection it is rather difficult to
judge. There is, however, abundant evidence to show
that Buy Cheap Metformin some sympathetic relation exists between the thy-
mus and thyreoid.
Beclard found an enlargement of the thyreoid after
extirpation of the thymus, and enlargement of the thy-
mus after extirpation of the thyreoid, in animals capable
of surviving the loss of these organs. As shown by Kund-
rat, enlargement of the thymus has been found in Base-
dow's disease by Mobius and by Spencer, and hyper-
trophy of lymph nodes, tjjnsils, and intestinal follicles
has been noted in the same disease by several observers
(White, Purchase Metformin Gowers). The liability to sudden cardiac paraly-
sis, which is often the prominent feature in the death
of subjects of the IjTiiphatic constitution, Generic Metformin finds Order Metformin at least
a partial counterpart in the persistent tachycardia of
Basedow's disease. Miiller believes that a congenital or
acquired neuropathic constitution is an essential ele-
ment in the production of exophthalmic goitre.
Exciting Causes and Planner of Death of Subjects
of the Lymphatic Constitution. — The majority of cases
thus far reported have died as the result of chloroform
narcosis. One case reported by Heusler died after ether
narcosis and the loss of considerable blood. Death may
apparently occur at any stage of the narcosis, during the
first few inhalations or even after apparent recovery from
the effects of the anaesthetic.
Two patients survived a first administration of chloro-
form to perish some months later during a second or third
operation.
The usual signs of danger may be observed; the pa-
tients may respond to treatment for a time, and a few fee-
ble respiratory movements may be elicited for some mo-
ments, or for a considerable period, or the cardiac and
respiratory paralysis may be instant and complete. In
all of these particulars these cases have presented no dis-
tinguishing peculiarities.
Seven reports by Nordmann and Paltauf refer to the
sudden death of persons who fell into the water, and al-
though immediately recovered were yet dead, or who
died suddenly while bathing.
In none of these cases were the ordinary signs of
death by drowning to be found, but the usual evidences
of the constitutio lymphatica were present.
Other persons died suddenly during the excitement
of card playing, or fell dead on the street while engaged
in ordinary exertions.
The sudden death of the young son of Professor
Langerhans, of Berlin, immediately after the injection
of a preventive dose of diphtheria antitoxine has called
forth considerable discussion as to the probable cause of
this sudden fatality, and has been variously explained
by Langerhans. Eulenberg, and Piirkhauser. Paltauf
suggests that this and other similar cases may find their
true explanation in the presence 'of the constitutio lym-
phatica.
It seems probable, from the considerations relating
especially to hypoplasia of the heart and arteries, that
some rapidly fatal forms of the infectious diseases, and
some sudden fatalities during convalescence from these
diseases, may be in part referable to the constitutio lym-
phatica.
It must be emphasized, however, that the data are as
yet entirely too Purchase Metformin Online limited to indicate definitely the scope
of the constitutio lymphatica, and until the observations
have been very considerably extended it will be well to
observe extreme caution before attributing miscellaneous
cases of sudden death to the lymphatic constitution.
The manner of death usually indicates a cardiac
paralysis, which may or may not be combined with imme-
diate failure of respiration. Of the chain of events by
which this result is reached Metformin Online little is known. That the
cardiac muscle in these subjects is specially susceptible
to the effects of chloroform may natvirally be supposed.
Very slight importance can at present be attached to the
mechanical irritation or pressure of the enlarged thymus.
We are therefore compelled to content ourselves with
the statement, very plainly supported by clinical expe- Cheap Metformin
rience with these cases, that the subjects of the Ij'm-
phatic constitution, for unknown reasons, are specially
susceptible to reflex cardiac paralysis.
The Diagnosis of the Lymphatic Constitution. — Since

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