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Related post: muth.
Dr. A. M. Vance asked what had killed the people.
August 1, 1891.]
PROCEEDINGS OF SOCIETIES.
135
Dr. OoTTELL said that tlie only theory, granting arsenic did
not kill them, that had anything like facts to support it, was
the ptomaine theory. Dr. Goodman had carried out a verj^ well
conducted theory of ptomaine. He had got some facts, and very
good ones, and the speaker would say that it was the best theory
he had seen.
Dr. J. A. OcHTEELONY (by invitation) said that he had been
very much interested, not only by the paper, so carefully writ-
ten and evincing such close observation, which Dr. Irwin had
read, but by all the remarks that had been made by Buy Nevirapine the gentle-
men taking part in tlie discussion. The whole affair had excited
the interest of the physicians throughout the city and, he was
sure, throughout the country, and not the least interesting was
that everybody who had had anything to do with it seemed
to be nearly as much in the dark now, if not more so, than
in the beginning. So far as he had been able to keep up
with the progress of tbe investigation, there seemed to be three
theories. One gentleman had attended some cases, and had
said that there had been nothing about them indicative of poi-
soning of any kind. They had been simply cases of cholera
morbus. He thought that opinion rather strange, when it was
a well-known fact that the different kinds of metallic poisoning
were all characterized by acute gastritis, and that, after all,
cholera morbus was nothing but irritation and congesrion.
Then the three different kinds of poisoning suggested — pto-
maine, mushroom, and arsenical poisoning. It was a very curi-
ous affair through and through. He believed about sixty-five
people had been poisoned, and out of that number six had died,
and he thought that only three post-mortem exaTuinations liad
been made. All seemed to have died at considerable periods
of time after the supposed poisoning had taken place. It had
occurred to him that, in the celebrated case he had seen re-
ported somewhere, death had taken place on the sixteenth day,
and it was a well-established fact that death had been the result
of arsenical poisoning, and yet no trace of arsenic had been
found on analysis. It did not seem to him that negative results
militated very much against the possibility that arsenic might
have been the cause of the trouble, and when he thought of the
ptomaine theory that had been alluded to by his distinguislicd
friend. Professor Cottell, he remembered several instances re-
corded by Brouardel and Botmy where ptomaines had been
found in the cases of persons proved to have died of arsenical
poisoning. There was no doubt at all of the existence of ar-
senical poisoning in these cases, yet ptomaines had been found.
The clinical phenomena seemed to have been very different
in the different cases, but that was what one expected — symp-
toms varied so much in regard to the quantities taken, accord-
ing to the emptiness of the stomach, according to the dilution
of the poison, according to the temperament, according to the
condition of the patient, whether asleep or awake, and accord-
ing to the preconceived notion of the observer. Bennett hud
said a long time ago that there were more false facts than
theories in medicine. And the further we traveled along the
journey of life, the more we realized that facts appeared very
different according to the medium through which they were
viewed, the point from whence they were viewed, and the ])re-
conceived notions of the individuals who observed the facts, and
he was satisfied in his own mind that perfectly honest men,
well-meaning, competent men, would see things very different-
ly. The time had long gone by with him when he was inclined
to quarrel with people because they did not see things as he
saw them. He was perfectly satisfied that they differed either
because they had some facts that he had not, or because he had
some facts that they had not, and, whicliever it was, there was no
reason for animadversion on either side. He must say that, look
ing at the matter from the standpoint of an outsider, he was un-
able to divest his mind of the idea that certainly the cases that
Dr. Irwin had reported must have been cases of arsenical poison-
ing. It was simply an opinion. Making all allowance for its un-
reliability, the symptomatology was very striking, and he must
say he did not see anything to conflict with that view, but, on
the other hand, everything to bear it out. The whole affair was
shrouded in mystery. Possibly one of these days it woald be
solved, but until then there would always be more or less doubt
and more or less uncertainty about it. All we could say was
that we had to judge by the facts before us. All the perfectly
reported and recorded facts that he had seen or knew anything
about were those furnished by Dr. Irwin, and he did not think
any one who had listened to that report could help being im-
pressed with the fact that these cases looked like arsenical poi-
soning. In addition to that, he had got Mr. Flexner's report that
arsenic had been found in the sublimate from the copper given
him and in the secretions from Dr. Anderson's patient; also the
post-mortem appearances given by Dr. Cottell, and from what
he had said relating to the condition of the mucous membrane in
the stomach of Mrs. Guthrie. Certainly those appearances must
have been produced by some cori'osive poison. Neither mush-
rooms nor ptomaines would produce such destructive lesions in
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